Endocrine Abstracts

A 48 year old man was reviewed in the late endocrine effect of childhood cancer treatment clinic. He was diagnosed with Acute Lymphoblastic Leukemia back in 1983, at the age of 9 and underwent chemotherapy with UKALL X regime, craniospinal irradiation, followed by total body irradiation and autologous bone marrow transplant the same year. Subsequently he was found to be growth hormone deficient 2 years later and by the age of 21 he developed hypopituitarism. In 2001, by the ag...

Case History: A 76 year old woman presented to the Accident & Emergency Department with persistent hypokalaemia, hypertension and metabolic alkalosis. She complained of ongoing muscle fatigue and tiredness and denied any headaches or vision problems. On examination, she had evidence of centripetal obesity, proximal myopathy, pink striae and bruises on her abdomen. No visual field deficit on confrontation and neurological examination was normal. She had a past medical histo...

A 69 year old lady was initially seen in clinic in August 2020 for a right adrenal incidentaloma which was discovered after she had a CT abdomen for diverticulitis related symptoms. She subsequently had a dedicated CT Adrenal in January 2019 before she was seen in clinic which showed a 25 x 32 mm right adrenal adenoma labelled as lipid poor with an absolute & relative washout of 67% and 47% respectively. Her past medical history included hypertension and anxiety disorder. ...

A 79-year-old female was admitted with general decline, polydipsia, polyuria, decreased appetite and constipation. Her family reported mobility decline over past six months and confusion over past few days with weight loss. She had hypertension on Amlodipine and renal impairment was only detected when she recently moved to UK from Jamaica. An incidental finding of hypercalcaemia was found with an adjusted calcium of 3.03, PTH 79.8, vitamin D 33 and phosphate 0.41. The initial ...

: A 26 year old 22 weeks pregnant woman was referred to the Endocrine team after she presented with high blood pressure without evidence of proteinuria. She had no past medical history and was newly diagnosed with gestational diabetes. On clinical examination, she had some clinical features consistent with hypercortisolism such as very prominent large purplish striae over her abdomen, bad facial acne, multiple superficial ecchymoses due to easy skin bruisability and excessive ...

Case History: A 46 year old lady presented to A&E with a 4 day history of headache, vomiting, abdominal pain and fever. On further questioning, she admitted to having had experienced occasional episodes of palpitations, hot flushes and headaches over the past few months. She had history of appendectomy when she was young and acoustic neuroma removal few years ago. She wasn’t on any regular medications. On clinical examination, she looked visibly unwell and was hypoxic...